Seth Godin posted about starting a local newspaper. Michael Rosnblum has suggested regional news centers. I listened to Richard Florida on CBC radio and he predicts just such macro regions if you listen.
It seems to me local is the new frontier... the new blue ocean.
How convenient. How exciting for many. There are many macro regions out there. The time to grab one is now. It will take work or you can watch as I try it out myself.
I suggest we become the story tellers in our region. Stories about our macro region relavent to our macro region for our our macro region.
Map your blue ocean for macro regional web news/docs and sail it!